CRP and alkaline phosphatase measurement: For the prediction of AP severity, the AUC values were 0.79 (CI 0.72–0.86) for BISAP, 0.80 (CI 0.76–0.85) for CTSI, 0.81 (CI 0.75–0.87) for the Ranson score, 0.83 (CI 0.75–0.91) for mCTSI, and 0.73 (CI 0.64–0.83) for CRP, with all tools showing comparable performance [12].