GPR137 and neoplasm: As previous study showed that, miR-134-3p expression is significantly induced in anisomycin-treated isolated human ovarian cancer tumor stem cells (HuOCSCs), which suppresses the elevated expression of GPR137, one of the genes specifically targeted for regulation by miR-134-3p, and restrains both the in vitro and in vivo activities of HuOCSCs [13], indicating a potential association between the expression levels of GPR137 and the development of OC, and also suggesting that GPR137 would be a promising target for compromise of HuOCSCs activity and a possible prognosis of OC development.