To finally test the oncogenic role of GPR137-RAB8A signal axis in OC progression in vivo, we established a SK-OV-3 cell line and an A2780 cell line that stably expressed GPR137-shRNA and RAB8A-shRNA by infection of levtiviruses carrying the shRNA sequences targeting GPR137 or RAB8A, respectively. Here, GPR137 is linked to infection.