COL6A3 and coronary artery disorder: BMI was associated with increased plasma levels of C-terminal COL6A3 (β = 0.06, 95% CI: 0.04–0.08, P = 8.5 × 10−12), and a standard deviation increase in plasma C-terminal COL6A3 levels increased the odds of CAD (OR = 1.34, 95% CI: 1.12–1.59, P = 1.1 × 10−3), consistent with the MR results.