However, this inflammatory biomarker may remain as a predictor for cardiovascular death and all-cause death during long-term follow-up.[33] The association between IL-6 and CAC has been demonstrated in multiple studies.[12,34] Specifically, higher IL-6 levels correlate with elevated CAC scores and progression of atherosclerosis, suggesting that IL-6 may be a potential biomarker for CAD and a marker of subclinical CVD.[13]. This evidence concerns the gene IL6 and atherosclerosis.