IL6ST and coronary artery disorder: Moreover, the study demonstrated that elevated level of IL-6 was associated with higher Gensini scores, and CAD patients exhibited higher concentrations of this biomarker and sIL-6Rα compared with healthy postmenopausal women.[46] In a separate investigation, researchers found that individuals with chronic or acute CAD showed notably lower levels of sgp130 in comparison to the control subjects without CAD.