In addition, they can be attracted to the tumor site through mechanisms dependent on CCR6/CCL20.[23] In addition, the presence of Th17 cells has been shown to inhibit proliferation and angiogenesis in HNSCC.[23] Further investigation into the mechanisms of Th17 cell differentiation and recruitment in HNSCC will help elucidate their role in promoting or inhibiting tumor progression. This evidence concerns the gene CCR6 and neoplasm.