ALB and focal segmental glomerulosclerosis: Primary FSGS is a heterogeneous group of clinical and pathological entities that are characterized by the full nephrotic syndrome, including nephrotic-range (>3.5 g/day protein) proteinuria [or even massive (>10 g/day) protein loss in the urine (72)] as well as reduced plasma albumin concentrations (hypoalbuminemia; <30 g/L) without the presence of genetic or secondary cause (10).