Then, the same mutational analysis was performed for cancer types exhibiting upregulation of IGFBP2, including BRCA (0.5%), GBM (0.3%), HNSC (1.6%), LUAD (0.6%), PRAD (1.1%), THCA (0%), and UCEC (1.6%) (Figure 5D). This evidence concerns the gene IGFBP2 and glioblastoma.