Next, we combined these 3 variables that resulted in an independent association with GIST genotype (SUVmax ≤5.75, gastric location, and tumor size >10 cm) in a clinical score to enhance their accuracy in discriminating PDGFRA-mutant from KIT exon 11–mutant GISTs, assigning 1 point to each of them (Table 3). This evidence concerns the gene KIT and gastrointestinal stromal tumor.