This leads to decreased nitrosylation of neuronal calcium calpain, activating cyclin‐dependent kinase‐5, and ultimately causing tau phosphorylation.[8] Additionally, dietary salt disrupts the tricarboxylic acid cycle, leading to excessive tau protein phosphorylation and synaptic dysfunction during aging.[9] Thus, the neuronal tau pathology, as seen in the AD brain, is critical to high‐salt diets‐induced memory decline.[10]. The gene discussed is MAPT; the disease is Alzheimer disease.