ZBP1 and cyst: Furthermore, Zbp1‐knockout mice exhibit a greater cyst burden and stronger inflammatory cytokine response during chronic infection compared to control mice.[29] Our previous study demonstrated that obvious apoptosis or necrotic apoptosis occur in the CNS of the hosts infected with AC,[30] however, physiological role of the ability of Zbp1 in the neuroparasitic infection remains to be elucidated.