NFKB1 and systemic lupus erythematosus: The inhibitory effect of A20 on CCL2 has been observed in multiple diseases, such as vitiligo [144], systemic lupus erythematosus (SLE) [145], and acute endoplasmic reticulum (ER) stress [146], and these studies all point to the fact that A20 downregulates CCL2 primarily by inhibiting the NF‐κB signaling pathway.