IKBKG and hepatocellular carcinoma: Similarly, upon ectopic expression of 3C in an OE system-based on transfection, we found that HAV 3C protease and its precursor 3CD diminished NEMO abundance by more than 50% in Huh7-Lunet cells, a widely used HCC-derived cell line (Fig. 3) but found no indication for functional significance of this cleavage in any of our models.