2.5. Enhanced Sensitivity of HCT-116 CRC Cells to EGF Was Caused by an Increase in EGFR Protein Levels Through Indoxyl Sulfate-Induced Activation of the AhR/c-Myc and Akt/β-Catenin/c-Myc Pathways. This evidence concerns the gene MYC and colorectal carcinoma.