GNRH1 and atrial fibrillation: This phenomenon can be explained by the higher plasma glucose levels promoted by the greater availability of AF [35], since glucose is an intrafollicular mediator that, at higher concentrations in the blood, promotes an increase in insulin-like growth factor 1 (IGF1) and inhibits the action of neuropeptide Y, which acts on the metabolic hormonal axis and stimulates the release of GnRH in the hypothalamus, which in turn increases FSH and LH pulses, thereby stimulating follicular growth [36].