FTO and colitis: Studies have shown that FTO in the brain can regulate postnatal growth in mice,24 memory processes in the prefrontal cortex and hippocampus,25 brain development, and adult neurogenesis.26 Moreover, FTO modulates colitis and alterations in gut microbiota in an m6A-dependent manner.27 All this evidence suggests that proteins related to m6A modification may serve as a platform for interactions between symbiotic bacteria and their host.