Furthermore, the increased immunoreactivity of resected GBM tissue for the FTL subunit is responsible for the synthesis of the FTL-type isoform, which corresponds well with the reported expression of FTL-type isoferritins in cultured glioblastoma multiforme-derived cells and similar findings in glioblastoma stem cells [104]. The gene discussed is FTL; the disease is glioblastoma.