In a cohort of >800 women analyzed for FPN-1 and hepcidin expression in breast cancer cells, independent of other breast cancer markers, high FPN-1/low hepcidin showed a 10-year survival of >90%, whereas women with low FPN-1 /high hepcidin expression showed a 10-year survival of only 43% [44]. The gene discussed is HAMP; the disease is breast cancer.