The results showed that compared with the control group (sh-NC), the number of α-SMA+ and CD31+ cells in lung metastases of OSTM1 knockdown-group (sh-OSTM1) mice was significantly reduced, suggesting that the knockdown of OSTM1 could inhibit angiogenesis in gastric-cancer lung metastases (Figure 3B). Here, OSTM1 is linked to gastric cancer.