On the other hand, we have GFAP as the main biomarker of astrogliosis for neurodegenerative and neurological diseases; thus, identifying specific GFAP proteoforms could result in testing for specific biomarkers of neurodegenerative diseases, by recognizing the expression of each isoforms that are characteristic of particular cellular processes [25]. The gene discussed is GFAP; the disease is neurodegenerative disease.