ADHD, anxiety disorder, and depressive disorder were associated with TSC1 rather than TSC2 (ADHD TSC1 = 17.6%; TSC2 = 16%, p = 0.6881; anxiety disorder TSC1 = 10.1%; TSC2 = 8.6%; p = 0.7809; depressive disorders TSC1 = 10%; TSC2 = 5.2%; p = 0.0509) [7] (de Vries et al., 2018). This evidence concerns the gene TSC1 and depressive disorder.