CUL7 and neoplasm: In 34 patients with HCC and seven different cell line samples analyzed by qRT-PCR and Western blot, Cul7 showed high expression, especially in metastatic tumor tissues; there was a negative correlation between Cul7 expression and long survival, and it was determined that migration, invasion, and metastatic properties were significantly reduced by silencing of Cul7 in liver cancer cells.