The absence of CK7 and EMA and the overexpression of E-cadherin and CD10 are helpful elements in differentiating renal carcinomas with Xp11.2 translocation from conventional clear cell renal carcinomas (CK7-, EMA+, E-cadherin-, CD10+) or papillary renal carcinomas (CK7+, E-cadherin+) [7]. This evidence concerns the gene CDH1 and clear cell renal carcinoma.