To test whether TIPE2 changes lipid peroxidation-related PE and PC species in MDSCs, we measured these PUFA-PLs and PUFA-ePLs in tumor MDSCs of Wild-type (WT) and TIPE2-deficient (TIPE2−/−) C57BL/6 mice bearing LLC (Lewis lung carcinoma) treated with IKE (the ferroptosis inducer widely used for in vivo research) by targeted phospholipid analysis using the HPLC-MS/MS system. Here, TIPE2 is linked to neoplasm.