CD33 and blood coagulation disease: However, when analyzing myeloid subpopulations, in CD14+/CD33+ classical monocytes, we observed a significant difference in the percentage of surface-bound FVIII levels in thrombosis patients versus HA patients (0.595% versus 0.058%, p = 0.0074), healthy subjects (0.07% versus 0.595%, p = 0.0093), and patients with other coagulopathies (0.12% versus 0.595%, p = 0.02) (Figure 5a).