Currently, several types of immunotherapies are recognized, including cancer vaccines (e.g., dendritic cell, peptide/protein, gene (35), viral (36), oncolytic viral (37), or repurposed viral vaccines) (35), monoclonal antibodies and checkpoint inhibitors (ICIs) (38), adoptive cell therapies (39, 40), and immunomodulators (e.g., cytokines, pattern recognition receptor (PRR) and stimulator of interferon genes (STING) agonists, and vaccine adjuvants) (41). This evidence concerns the gene STING1 and cancer.