Additionally, age (p < 0.001), diabetes (p < 0.001), hypertension (p = 0.216), cancer (p = 0.005), diastolic blood pressure (p = 0.038), GCS (p < 0.001), ISS (p < 0.001), SOFA (p < 0.001), SAH (p = 0.040), platelet (p = 0.016), RBC (p < 0.001), hemoglobin (p < 0.001), glucose (p < 0.001), and prothrombin time (p = 0.006) were significantly associated with TBI mortality. The gene discussed is F2; the disease is hypertensive disorder.