Exosomal miRNAs (miR-21, miR-378e, and miR-143), transferred from CAF to breast cancer cells, have been found to promote EMT and stemness, which are characterized by higher levels of EMT markers (snail and zeb) and BCSC markers (oct3/4, nanog, and sox2) (52). This evidence concerns the gene ZEB1 and breast carcinoma.