In a mouse model of pulmonary fibrosis, Leucine-Rich Repeat Kinase 2 (LRRK2) expression is significantly reduced in alveolar type II epithelial (ATII) cells, and LRRK2-deficient ATII cells exhibit an enhanced ability to recruit profibrotic macrophages via the CCL2/CCR2 axis. Here, LRRK2 is linked to pulmonary fibrosis.