Notably, CD8+ T-cells from PP-MS patients exhibited a substantial increase in GM-CSF (+0.42%; p < 0.01) and TNF-α (+0.34%; p = 0.03) levels compared to HCs, while RR-SMS patients had a significant increase in GM-CSF levels (+0.30%; p = 0.02) compared to HCs. This evidence concerns the gene CD8A and myeloid sarcoma.