PLA2G7 and Alzheimer disease: In female AD patients, the areas under the ROC curves for AC and AC + Lp-PLA2 were 0.764 and 0.925, respectively, and for DC, DR2, DR4, DR8, Lp-PLA2, and the combined five-variable diagnosis were 0.810, 0.665, 0.876, 0.897, 0.852, and 0.985, respectively (Supplementary Figures S1C,D), suggesting that these biomarkers did not show sex difference in diagnostic capabilities in the current study.