The rs312457 genotype of the SLC16A13 gene was associated with the occurrence of diabetes in a Chinese population (Zheng et al., 2021).The knockdown of Slc16a13 ameliorated hepatic lipid accumulation and insulin resistance in mice (Schumann et al., 2021), indicating that SLC16A13 may be a potential therapeutic target for both T2D and NAFLD. This evidence concerns the gene SLC16A13 and type 2 diabetes mellitus.