POMC and Hypsarrhythmia: The proportion of hypsarrhythmia resolution following ACTH therapy was greater in patients with an age of onset of 3–6 months (p = 0.013), within this group, 5.6% were treated with ACTH only, 94.4% were treated with ACTH and Asms, No significant difference was observed among the three groups of patients aged 3–6 months treated with ACTH alone, and ACTH plus ASMs.