CTP: Child-Turcotte-Pugh, CLD: chronic liver disease, HCV: hepatitis C virus, HBV: hepatitis B virus, NAFLD: non-alcoholic fatty liver disease, ALT: alanine aminotransferase, AST: aspartate aminotransferase, BMI: Body Mass Index, INR: International Normalized Ratio, PT: prothrombin time. The gene discussed is F2; the disease is congenital secretory chloride diarrhea 1.