With time, it can be observed that the research focus has gradually shifted from “focal segmental glomerulosclerosis,” “podocyte function” to “therapeutic target,” and “NLRP3 inflammasome.” From the above analysis, we speculate that the future research hotspots of autophagy in podocytopathies field are related to identify novel therapeutic targets for the prevention and treatment of podocytopathies, as well as explore the role of inflammation in the progression of podocytopathies. Here, NLRP3 is linked to focal segmental glomerulosclerosis.