Significant predictors of respiratory failure in children with MPP included CRP (OR ═ 1.013, 95% CI ═ 1.002–1.025), IL-10 (OR ═ 1.034, 95% CI ═ 1.002–1.068), APTT (OR ═ 1.095, 95% CI ═ 1.009–1.187), D-dimer (OR ═ 1.287, 95% CI ═ 1.081–1.532), and HB (OR ═ 0.972, 95% CI ═ 0.941–0.998) (P < 0.05) (Figure 2A). Here, CRP is linked to respiratory failure.