DEA revealed similar expression profiles between the MDS patients and controls, with only a few differentially expressed TEs (FDR < 0.05) [11 upregulated TEs (ERV1: HERV-Fc1, MER51E, LTR27E, MER65C, HUERS-P1, PABL_A, and LOR1I; ERV3: MER54B and LTR75; CR1: X5A_LINE, SINE: MIR3) and two downregulated TEs (ERV1: LTR71A and LTR26E)] in the MDS group (SI Fig. 2). The gene discussed is CR1; the disease is myelodysplastic syndrome.