These TERT-related liver diseases were marked by fibrosis, cirrhosis, and non-cirrhotic portal hypertension, the latter of which was featured by nodular regenerative hyperplasia, incomplete septal fibrosis, and CD34-positive sinusoidal endothelial cells, indicating an abnormal proportion of arterial blood flow to the sinuses [22, 24]. This evidence concerns the gene TERT and liver disorder.