The cluster of differentiation 147 (CD147) receptor, a highly glycosylated Type 1 transmembrane glycoprotein of the immunoglobulin superfamily and prominent matrix metalloproteinase (MMP) inducer, is one of several receptors for the SARS-CoV-2 spike protein that mediate viral infection of host cells [12] and may be downregulated by the GLP-1 agonist Exenatide. The gene discussed is GCG; the disease is viral infectious disease.