WAS is a combined immunodeficiency disorder characterized by thrombocytopenia, and it primarily affects males with dysfunctional platelets due to defects in the WAS protein (WASp) that lead to bleeding problems and severe recurrent infections, with an incidence rate of between 1 and 10 in 1 million [26,27,28]. The gene discussed is WAS; the disease is Wiskott-Aldrich syndrome.