In addition, the rats in the Fructose/STZ-induced diabetes group showed a noticeable rise in G6P activity in hepatic tissues in relation to the control rats as shown in Figure 4D. In contrast, diabetic rats receiving QCT and SS demonstrated a notable increase in hepatic HK, GK, and G6Pd activity in contrast to Fructose/STZ-induced rats. This evidence concerns the gene GK and diabetes mellitus.