In human hepatoma cells (HepG2), exposure to PFOA and PFOS resulted in an increase in the activity of superoxide dismutase (SOD) and catalase (CAT), as reported by Bonato et al. (2020) [41] in a review of findings on PFAS affecting oxidative stress biomarkers in vitro and in vivo. The gene discussed is CAT; the disease is hepatocellular carcinoma.