To evaluate whether TCR-001–transduced allogeneic T cells could specifically kill human pancreatic cancer organoids, TCR-001–transduced allogeneic T cells or mock T cells were cocultured with human pancreatic cancer organoids naturally expressing KRAS G12 mutations with or without natural HLA-A*11:01 expression on rat tail collagen–coated plates. This evidence concerns the gene KRAS and familial pancreatic carcinoma.