We defined clusters corresponding to melanoma (PMEL, MLANA), immune infiltrates (TRBC2, TRAC, TMSB4X), melanophages (CD74, LYZ), keratinocytes (KRT14, TRIM29), blood vessels (CAVIN1, PECAM), and fibroblast‐enriched areas in the dermis (DCN, COL1A2, FBLN1). Here, TRIM29 is linked to melanoma.