We defined clusters corresponding to melanoma (PMEL, MLANA), immune infiltrates (TRBC2, TRAC, TMSB4X), melanophages (CD74, LYZ), keratinocytes (KRT14, TRIM29), blood vessels (CAVIN1, PECAM), and fibroblast‐enriched areas in the dermis (DCN, COL1A2, FBLN1). The gene discussed is CD74; the disease is melanoma.