We defined clusters corresponding to melanoma (PMEL, MLANA), immune infiltrates (TRBC2, TRAC, TMSB4X), melanophages (CD74, LYZ), keratinocytes (KRT14, TRIM29), blood vessels (CAVIN1, PECAM), and fibroblast‐enriched areas in the dermis (DCN, COL1A2, FBLN1). Here, PMEL is linked to melanoma.