We defined clusters corresponding to melanoma (PMEL, MLANA), immune infiltrates (TRBC2, TRAC, TMSB4X), melanophages (CD74, LYZ), keratinocytes (KRT14, TRIM29), blood vessels (CAVIN1, PECAM), and fibroblast‐enriched areas in the dermis (DCN, COL1A2, FBLN1). This evidence concerns the gene TRBC2 and melanoma.