We defined clusters corresponding to melanoma (PMEL, MLANA), immune infiltrates (TRBC2, TRAC, TMSB4X), melanophages (CD74, LYZ), keratinocytes (KRT14, TRIM29), blood vessels (CAVIN1, PECAM), and fibroblast‐enriched areas in the dermis (DCN, COL1A2, FBLN1). The gene discussed is LYZ; the disease is melanoma.