Additionally, various monocyte cell populations (NcMono, cMono, and IntMono) demonstrated a reduced ability to produce inflammatory cytokines such as IL-1β, IL6, IL12, TNFα (Supplementary Figures 3C–E, G, H) and macrophage inflammatory chemokines (MIP1β, MCP1) (Supplementary Figures 3B–F) in both COVID and LC patients compared to unexposed HD or Recovered subjects. This evidence concerns the gene IL1B and laryngotracheoesophageal cleft.