CD38 and amyotrophic lateral sclerosis: Regarding other clinical variables associated with ALS, weight loss was an independent factor in decreasing CD38+Treg concentrations (MR=0.404, 95%CI 0.188-0.869,p=0.020), while age at onset influenced CD39+Tregs(%) over total Tregs (MR=1.251,95%CI 1.026;1.526, p=0.027).