PKP2 and cardiac arrhythmia: Current research projects include the Adeno-associated virus serotype 9 (AAV9): PKP2 gene therapy project, the TN-401 AAV9-Based Gene Therapy for PKP2-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC), etc. These treatments prevent ventricular remodeling, delay the decline in left ventricular function, and reduce the incidence of arrhythmias.