In addition, the results of Jiang et al. (2011) also confirmed that ginsenoside Rg3 alone or in combination with CTX induced apoptosis in HCC cells by activating an intrinsic pathway and altering the expression of the Bcl-2 family of proteins, which inhibited tumor growth in vivo and prolonged the survival in mice (Jiang et al., 2011). This evidence concerns the gene BCL2 and hepatocellular carcinoma.