CASP3 and colorectal carcinoma: Interestingly, evidence from prior studies clearly suggests that ginsenosides, such as Rg3, CK, and Rh2, and other substances can suppress the growth of tumor cells and trigger apoptosis of CRC cells by increasing caspase-3 expression (Han et al., 2016; Yang et al., 2017; Zhang et al., 2013).