As a result, in the current study, we further investigated the function and mechanism of TMG against colorectal cancer by investigating their impact on the survival and apoptotic rate of CT26.WT cells in vitro and protein levels of the Raf/MEK/ERK pathway and apoptotic factor Bax/Bcl-2/caspase-3 in a colorectal cancer mouse model. This evidence concerns the gene MAP2K7 and colorectal cancer.