GDF15 and dementia: For example, a recent study has linked the plasma levels of glial fibrillary acidic protein (GFAP), neurofilament light (NfL), growth differentiation factor 15 and latent transforming growth factor beta binding protein 2 with dementia.37 By integrating multiple blood-based biomarkers, the accuracy of identifying individuals at high risk for dementia can be improved, thereby facilitating early intervention efforts.