COL11A1 and breast cancer: Remarkably, the average COL11A1 mRNA expression in primary breast cancer samples (n = 107) was found to be 67.4 times greater than that in normal samples (n = 30, p < 0.001) and 25 times higher than in benign tumor samples (n = 30, p < 0.001), detailed in Figures 3(a) and 3(c).