AGO2 and Zika virus infectious disease: In cells that were not infected with BinJV or BinJ-ZIKV, ZIKV grew to similar titers in both cell types (1.4 × 108 TCID50/ml and 1.5 × 108 TCID50/ml at 4 days post ZIKV infection for Aag2 and Ago2-deficient Aag2, respectively) (Fig. 6A).