As per the findings from GEPIA, the box plot indicated that there were no differences in the expression of CDKN1B messenger RNA (mRNA) between normal and tumor tissues in colon cancer (p > 0.05) (Supplementary Figure S4A) and rectal cancer (p > 0.05) (Supplementary Figure S5A). Here, CDKN1B is linked to malignant colon neoplasm.