According to the findings from UALCAN, the box plot based on 283 patients with colon cancer (p > 0.05) (Supplementary Figure S6A) and 162 patients with rectal cancer (p > 0.05) (Supplementary Figure S7A) indicated that there was no significant correlation between the expression level of CDKN1B mRNA and lymph node metastasis. Here, CDKN1B is linked to malignant colon neoplasm.